Vitamin E Improves Doxorubicin Induced Nephrotoxicity; Possible Underlying Mechanisms
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چکیده
منابع مشابه
Vitamin C Ameliorates Acrylamide-Induced Nephrotoxicity and Improves the Biochemical Parameters in Rats
Background and Objective: Acrylamide is a highly soluble, widely- produced industrial and cytotoxic material. Some substances with antioxidant properties can ameliorate the deleterious effect of acrylamide. Vitamin C is necessary for the normal functioning of all cells and scavenging the free radicals due to the antioxidant properties. The present study was aimed to evaluate the effect of vitam...
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Introduction. Nephrotoxicity is one of the important side effects of anthracycline antibiotics. The aim of this study was to investigate the effects of nicotinamide (NAD), an antioxidant agent, against nephrotoxicity induced by doxorubicin (DXR). Methods. The rats were divided into control, NAD alone, doxorubicin (20 mg/kg, i.p.) and DXR plus NAD (200 mg/kg, i.p.) groups. At the end of the 10th...
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The specificity of gentamicin for vitamin E deficiency-associated oxidative stresses in the renal proximal convoluted tubules is apparently related to its ability to increasingly facilitate generation of radical species in mitochondria. To determine the ways in which vitamin E manage the currently processes, we conducted a prospective study aimed to investigate the tubular preserving effect of ...
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experimental animals. But which occurs first and is more important? Put another way, do patients with bupivacaine toxicity die of arrhythmias, contractile failure, or a combination of the two? Epinephrine is a first-line agent for treating cardiac arrest; but why patients who have undergone bupivacaine induced cardiac arrest are often resistant to adrenergic therapy? This article reviews the me...
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ژورنال
عنوان ژورنال: The Medical Journal of Cairo University
سال: 2018
ISSN: 2536-9806
DOI: 10.21608/mjcu.2018.55380